Formulation development and optimization of palm kernel oil esters-based nanoemulsions containing sodium diclofenac

Response surface methodology was employed to study the effect of formulation composition variables, water content (60%–80%, w/w) and oil and surfactant (O/S) ratio (0.17–1.33), as well as high-shear emulsification conditions, mixing rate (300–3,000 rpm) and mixing time (5–30 minutes) on the properti...

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Bibliografiske detaljer
Main Authors: Rezaee, Malahat, Basri, Mahiran, Rahman, Raja Noor Zaliha Raja Abdul, Salleh, Abu Bakar, Chaibakhsh, Naz, Karjiban, Roghayeh Abedi
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2014
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901780/
https://ncbi.nlm.nih.gov/pubmed/24531324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S49616
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