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Formulation development and optimization of palm kernel oil esters-based nanoemulsions containing sodium diclofenac
Response surface methodology was employed to study the effect of formulation composition variables, water content (60%–80%, w/w) and oil and surfactant (O/S) ratio (0.17–1.33), as well as high-shear emulsification conditions, mixing rate (300–3,000 rpm) and mixing time (5–30 minutes) on the properti...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Dove Medical Press
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3901780/ https://ncbi.nlm.nih.gov/pubmed/24531324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S49616 |
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