Tissue inhibitor of matrix metalloproteinases-1 loaded poly(lactic-co-glycolic acid) nanoparticles for delivery across the blood–brain barrier

AIM: The aim of this study was to develop poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) for delivery of a protein – tissue inhibitor of matrix metalloproteinases 1 (TIMP-1) – across the blood–brain barrier (BBB) to inhibit deleterious matrix metalloproteinases (MMPs). MATERIALS AND METHOD...

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Detalhes bibliográficos
Main Authors: Chaturvedi, Mayank, Molino, Yves, Sreedhar, Bojja, Khrestchatisky, Michel, Kaczmarek, Leszek
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901738/
https://ncbi.nlm.nih.gov/pubmed/24531257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S54750
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