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Effects of Molecular Weight and Loading on Matrix Metalloproteinase-2 Mediated Release from Poly(Ethylene Glycol) Diacrylate Hydrogels

Herein, we report on continued efforts to understand an implantable poly(ethylene glycol) diacrylate (PEGDA) hydrogel drug delivery system that responds to extracellular enzymes, in particular matrix metalloproteinase-2 (MMP-2) to provide controlled drug delivery. By attaching peptide as pendant gro...

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Detalhes bibliográficos
Main Authors: Ross, Amy E., Tang, Mary Y., Gemeinhart, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385811/
https://ncbi.nlm.nih.gov/pubmed/22535508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9356-3
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