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Phenylephrine induces elevated RhoA activation and smooth muscle α-actin expression in Pkd2+/− vascular smooth muscle cells

The mechanisms underlying vascular complications in autosomal-dominant polycystic kidney disease (ADPKD) have not been fully elucidated. However, molecular components altered in Pkd mutant vascular smooth muscle cells (VSMCs) are gradually being identified. Pkd2(+/−) arterial smooth muscles show ele...

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Main Authors: Du, Hui, Wang, Xiangling, Wu, Jun, Qian, Qi
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901428/
https://ncbi.nlm.nih.gov/pubmed/19893564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hr.2009.173
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