Analysis of Changes in Hepatic Gene Expression in a Murine Model of Tolerance to Acetaminophen Hepatotoxicity (Autoprotection)

Pretreatment of mice with a low hepatotoxic dose of acetaminophen (APAP) results in resistance to a subsequent, higher dose of APAP. This mouse model, termed APAP autoprotection was used here to identify differentially expressed genes and cellular pathways that could contribute to this development o...

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Detalhes bibliográficos
Main Authors: O’Connor, Meeghan A, Koza-Taylor, Petra, Campion, Sarah N, Aleksunes, Lauren M, Gu, Xinsheng, Enayetallah, Ahmed E., Lawton, Michael P, Manautou, José E
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901410/
https://ncbi.nlm.nih.gov/pubmed/24126418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.09.025
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