Synthetic Self-Assembling Clostridial Chimera for Modulation of Sensory Functions

[Image: see text] Clostridial neurotoxins reversibly block neuronal communication for weeks and months. While these proteolytic neurotoxins hold great promise for clinical applications and the investigation of brain function, their paralytic activity at neuromuscular junctions is a stumbling block....

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Bibliografiska uppgifter
Huvudupphovsmän: Ferrari, Enrico, Gu, Chunjing, Niranjan, Dhevahi, Restani, Laura, Rasetti-Escargueil, Christine, Obara, Ilona, Geranton, Sandrine M., Arsenault, Jason, Goetze, Tom A., Harper, Callista B., Nguyen, Tam H., Maywood, Elizabeth, O’Brien, John, Schiavo, Giampietro, Wheeler, Daniel W., Meunier, Frederic A., Hastings, Michael, Edwardson, J. Michael, Sesardic, Dorothea, Caleo, Matteo, Hunt, Stephen P., Davletov, Bazbek
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2013
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901392/
https://ncbi.nlm.nih.gov/pubmed/24011174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc4003103
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