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Synthetic Self-Assembling Clostridial Chimera for Modulation of Sensory Functions

[Image: see text] Clostridial neurotoxins reversibly block neuronal communication for weeks and months. While these proteolytic neurotoxins hold great promise for clinical applications and the investigation of brain function, their paralytic activity at neuromuscular junctions is a stumbling block....

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Bibliografische gegevens
Hoofdauteurs: Ferrari, Enrico, Gu, Chunjing, Niranjan, Dhevahi, Restani, Laura, Rasetti-Escargueil, Christine, Obara, Ilona, Geranton, Sandrine M., Arsenault, Jason, Goetze, Tom A., Harper, Callista B., Nguyen, Tam H., Maywood, Elizabeth, O’Brien, John, Schiavo, Giampietro, Wheeler, Daniel W., Meunier, Frederic A., Hastings, Michael, Edwardson, J. Michael, Sesardic, Dorothea, Caleo, Matteo, Hunt, Stephen P., Davletov, Bazbek
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2013
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901392/
https://ncbi.nlm.nih.gov/pubmed/24011174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc4003103
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