Synthetic Self-Assembling Clostridial Chimera for Modulation of Sensory Functions

[Image: see text] Clostridial neurotoxins reversibly block neuronal communication for weeks and months. While these proteolytic neurotoxins hold great promise for clinical applications and the investigation of brain function, their paralytic activity at neuromuscular junctions is a stumbling block....

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Hlavní autoři: Ferrari, Enrico, Gu, Chunjing, Niranjan, Dhevahi, Restani, Laura, Rasetti-Escargueil, Christine, Obara, Ilona, Geranton, Sandrine M., Arsenault, Jason, Goetze, Tom A., Harper, Callista B., Nguyen, Tam H., Maywood, Elizabeth, O’Brien, John, Schiavo, Giampietro, Wheeler, Daniel W., Meunier, Frederic A., Hastings, Michael, Edwardson, J. Michael, Sesardic, Dorothea, Caleo, Matteo, Hunt, Stephen P., Davletov, Bazbek
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2013
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901392/
https://ncbi.nlm.nih.gov/pubmed/24011174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc4003103
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