Trapping of the beta-adrenergic receptor in the hormone-induced state.
Isoproterenol and other agonists readily dissociate from the beta-adrenergic receptor in turkey erythrocyte membranes. However, when a low concentration of deoxycholate is added, the receptor locks the prebound agonist; i.e., the rate of dissociation of the prebound agonist decreases drastically. Th...
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| Publicat a: | Proc Natl Acad Sci U S A |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1983
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390129/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6314327/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.21.6441 |
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