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Ex Vivo Gene Delivery to Hepatocytes: Techniques, Challenges, and Underlying Mechanisms

Gene delivery to primary hepatocytes is an important tool for a number of applications including the study of liver cell biology and pathology, drug screening, and gene therapy. Robust transfection of primary hepatocytes, however, is significantly more difficult to achieve than in cell lines or read...

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Autors principals: Gao, Shan, Seker, Erkin, Casali, Monica, Wang, Fangjing, Bale, Shyam Sundhar, Price, Gavrielle M., Yarmush, Martin L.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901163/
https://ncbi.nlm.nih.gov/pubmed/22484829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-012-0555-y
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