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Cytomegalovirus (CMV)-Specific Perforin and Granzyme B ELISPOT Assays Detect Reactivation of CMV Infection in Inflammatory Bowel Disease

The role of cytomegalovirus (CMV) infection in the pathogenesis and exacerbation of Inflammatory Bowel Disease (IBD) has been unresolved. Typically, the CMV genome remains dormant in infected cells, but a breakdown of immune surveillance can lead to re-activation of viral replication in the gut muco...

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Detalhes bibliográficos
Main Authors: Nowacki, Tobias M., Bettenworth, Dominik, Ross, Matthias, Heidemann, Jan, Lehmann, Paul V., Lügering, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901090/
https://ncbi.nlm.nih.gov/pubmed/24710412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells1020035
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