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Granzyme B ELISPOT assay to measure influenza-specific cellular immunity

The immunogenicity and efficacy of influenza vaccination is markedly lower in the elderly. Granzyme B (GrzB), quantified in fresh cell lysates, has been suggested to be a marker of cytotoxic T lymphocyte (CTL) response and a predictor of influenza illness among vaccinated older individuals. We have...

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Autors principals: Salk, Hannah M., Haralambieva, Iana H., Ovsyannikova, Inna G., Goergen, Krista M., Poland, Gregory A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840047/
https://ncbi.nlm.nih.gov/pubmed/24055591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2013.09.007
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