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Core fucosylation and IgG function in NAIT

In this issue of Blood, Kapur et al show that maternal human platelet-specific antigen 1a (HPA 1a)-specific antibodies causing neonatal alloimmune thrombocytopenia (NAIT) possess oligosaccharides that are deficient in “core fucose” residues and appear to be more effective than fucosylated antibodies...

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Detalles Bibliográficos
Autor Principal: Aster, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901063/
https://ncbi.nlm.nih.gov/pubmed/24458274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-12-539965
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