Identification of Inhibitors of Triacylglyceride Accumulation in Muscle Cells: Comparing HTS Results from 1536-well Plate-Based and High-Content Platforms

Excess caloric consumption leads to triacylglyceride (TAG) accumulation in tissues that do not typically store fat, such as skeletal muscle. This ectopic accumulation alters cells, contributing to the pathogenesis of metabolic syndrome, a major health problem worldwide. We developed a 1536-well assa...

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Main Authors: Sugarman, Eliot, Koo, Ada, Suyama, Eigo, Ruidiaz, Manuel E., Heynen-Genel, Susanne, Nguyen, Kevin H., Vasile, Stefan, Soundarapandian, Mangala M., Vega, Rick B., Kelly, Daniel P., Smith, Layton H., Malany, Siobhan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901053/
https://ncbi.nlm.nih.gov/pubmed/23989452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057113501198
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