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Non-invasive In-cell Determination of Free Cytosolic [NAD(+)]/[NADH] Ratios Using Hyperpolarized Glucose Show Large Variations in Metabolic Phenotypes

Accumulating evidence suggest that the pyridine nucleotide NAD has far wider biological functions than its classical role in energy metabolism. NAD is used by hundreds of enzymes that catalyze substrate oxidation and, as such, it plays a key role in various biological processes such as aging, cell d...

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書誌詳細
主要な著者: Christensen, Caspar Elo, Karlsson, Magnus, Winther, Jakob R., Jensen, Pernille Rose, Lerche, Mathilde H.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900977/
https://ncbi.nlm.nih.gov/pubmed/24302737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.498626
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