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ADP-dependent Conformational Changes Distinguish Mycobacterium tuberculosis SecA2 from SecA1

In bacteria, most secreted proteins are exported through the SecYEG translocon by the SecA ATPase motor via the general secretion or “Sec” pathway. The identification of an additional SecA protein, particularly in Gram-positive pathogens, has raised important questions about the role of SecA2 in bot...

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Autores principales: D'Lima, Nadia G., Teschke, Carolyn M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900974/
https://ncbi.nlm.nih.gov/pubmed/24297168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.533323
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