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ADP-dependent Conformational Changes Distinguish Mycobacterium tuberculosis SecA2 from SecA1
In bacteria, most secreted proteins are exported through the SecYEG translocon by the SecA ATPase motor via the general secretion or “Sec” pathway. The identification of an additional SecA protein, particularly in Gram-positive pathogens, has raised important questions about the role of SecA2 in bot...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3900974/ https://ncbi.nlm.nih.gov/pubmed/24297168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.533323 |
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