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Structural Determinants for the Interaction of Formyl Peptide Receptor 2 with Peptide Ligands
Unlike formyl peptide receptor 1 (FPR1), FPR2/ALX (FPR2) interacts with peptides of diverse sequences but has low affinity for the Escherichia coli-derived chemotactic peptide fMet-Leu-Phe (fMLF). Using computer modeling and site-directed mutagenesis, we investigated the structural requirements for...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3900973/ https://ncbi.nlm.nih.gov/pubmed/24285541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.509216 |
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