A Role for Peroxisome Proliferator-activated Receptor γ Coactivator 1 (PGC-1) in the Regulation of Cardiac Mitochondrial Phospholipid Biosynthesis

The energy demands of the adult mammalian heart are met largely by ATP generated via oxidation of fatty acids in a high capacity mitochondrial system. Peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)-α and -β serve as inducible transcriptional coregulators of genes involved in mito...

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Autores principales: Lai, Ling, Wang, Miao, Martin, Ola J., Leone, Teresa C., Vega, Rick B., Han, Xianlin, Kelly, Daniel P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Lipids
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900969/
https://ncbi.nlm.nih.gov/pubmed/24337569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.523654
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