Molecular mechanisms of human hemoglobin switching: selective undermethylation and expression of globin genes in embryonic, fetal, and adult erythroblasts.

The globin chain synthetic pattern and the extent of DNA methylation within embryonic, fetal, and adult beta-like globin gene domains were evaluated in greater than or equal to 90% purified human erythroblasts from yolk sacs and fetal livers in the 6- to 12-wk gestational period as well as from adul...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Mavilio, F, Giampaolo, A, Carè, A, Migliaccio, G, Calandrini, M, Russo, G, Pagliardi, G L, Mastroberardino, G, Marinucci, M, Peschle, C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1983
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390095/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6316333/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.22.6907
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