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Multiple Roles of the SO(4)(2−)/Cl(−)/OH(−) Exchanger Protein Slc26a2 in Chondrocyte Functions

Mutations in the SO(4)(2−)/Cl(−)/OH(−) exchanger Slc26a2 cause the disease diastrophic dysplasia (DTD), resulting in aberrant bone development and, therefore, skeletal deformities. DTD is commonly attributed to a lack of chondrocyte SO(4)(2−) uptake and proteoglycan sulfation. However, the skeletal...

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Detalhes bibliográficos
Main Authors: Park, Meeyoung, Ohana, Ehud, Choi, Soo Young, Lee, Myeong-Sok, Park, Jong Hoon, Muallem, Shmuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900949/
https://ncbi.nlm.nih.gov/pubmed/24302720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.503466
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