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Solute Carrier Family 26 Member a2 (Slc26a2) Protein Functions as an Electroneutral SO(4)(2−)/OH(−)/Cl(−) Exchanger Regulated by Extracellular Cl(−)

Slc26a2 is a ubiquitously expressed SO(4)(2−) transporter with high expression levels in cartilage and several epithelia. Mutations in SLC26A2 are associated with diastrophic dysplasia. The mechanism by which Slc26a2 transports SO(4)(2−) and the ion gradients that mediate SO(4)(2−) uptake are poorly...

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Detalhes bibliográficos
Main Authors: Ohana, Ehud, Shcheynikov, Nikolay, Park, Meeyoung, Muallem, Shmuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281620/
https://ncbi.nlm.nih.gov/pubmed/22190686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.297192
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