Systemic delivery of miR-126 by miRNA-loaded Bubble liposomes for the treatment of hindlimb ischemia

Currently, micro RNA (miRNA) is considered an attractive target for therapeutic intervention. A significant obstacle to the miRNA-based treatments is the efficient delivery of miRNA to the target tissue. We have developed polyethylene glycol-modified liposomes (Bubble liposomes (BLs)) that entrap ul...

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Autors principals: Endo-Takahashi, Yoko, Negishi, Yoichi, Nakamura, Arisa, Ukai, Saori, Ooaku, Kotomi, Oda, Yusuke, Sugimoto, Katsutoshi, Moriyasu, Fuminori, Takagi, Norio, Suzuki, Ryo, Maruyama, Kazuo, Aramaki, Yukihiko
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900923/
https://ncbi.nlm.nih.gov/pubmed/24457599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03883
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