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Activation of membrane estrogen receptors attenuates opioid receptor-like1 receptor-mediated antinociception via an ERK-dependent non-genomic mechanism

To our knowledge, the present data are the first to demonstrate that activation of membrane estrogen receptors (mERs) abolishes opioid receptor-like 1 (ORL1) receptor - mediated analgesia via extracellular signal-regulated kinase (ERK)-dependent non-genomic mechanisms. Estrogen was shown previously...

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Hlavní autoři: Small, Keri M., Nag, Subodh, Mokha, Sukhbir S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900883/
https://ncbi.nlm.nih.gov/pubmed/24452062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2013.10.034
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