Differential effects on KCC2 expression and spasticity of ALS and traumatic injuries to motoneurons

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease manifested by progressive muscle atrophy and paralysis due to the loss of upper and lower motoneurons (MN). Spasticity appears in ALS patients leading to further disabling consequences. Loss of the inhibitory tone induced by downregu...

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Bibliografiska uppgifter
Huvudupphovsmän: Mòdol, Laura, Mancuso, Renzo, Alé, Albert, Francos-Quijorna, Isaac, Navarro, Xavier
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2014
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900854/
https://ncbi.nlm.nih.gov/pubmed/24478630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00007
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