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Biosynthesis of renin: multiplicity of active and intermediate forms.

Processing of renin involves sequential proteolytic cleavages of a preproform to the active mature forms. Preprorenin is rapidly internalized cotranslationally into the rough endoplasmic reticulum and hydrolyzed by signal peptidase to produce prorenin. In the Golgi, prorenin is converted (within 15...

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Detalhes bibliográficos
Main Authors: Pratt, R E, Ouellette, A J, Dzau, V J
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC390075/
https://ncbi.nlm.nih.gov/pubmed/6139811
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