Absence of Intestinal PPARγ Aggravates Acute Infectious Colitis in Mice through a Lipocalin-2–Dependent Pathway

To be able to colonize its host, invading Salmonella enterica serovar Typhimurium must disrupt and severely affect host-microbiome homeostasis. Here we report that S. Typhimurium induces acute infectious colitis by inhibiting peroxisome proliferator-activated receptor gamma (PPARγ) expression in int...

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Detalhes bibliográficos
Main Authors: Kundu, Parag, Ling, Teo Wei, Korecka, Agata, Li, Yinghui, D'Arienzo, Rossana, Bunte, Ralph M., Berger, Thorsten, Arulampalam, Velmurugesan, Chambon, Pierre, Mak, Tak Wah, Wahli, Walter, Pettersson, Sven
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900641/
https://ncbi.nlm.nih.gov/pubmed/24465207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003887
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