A Critical Role for Thioredoxin-Interacting Protein in Diabetes-Related Impairment of Angiogenesis

Impaired angiogenesis in ischemic tissue is a hallmark of diabetes. Thioredoxin-interacting protein (TXNIP) is an exquisitely glucose-sensitive gene that is overexpressed in diabetes. As TXNIP modulates the activity of the key angiogenic cytokine vascular endothelial growth factor (VEGF), we hypothe...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dunn, Louise L., Simpson, Philippa J.L., Prosser, Hamish C., Lecce, Laura, Yuen, Gloria S.C., Buckle, Andrew, Sieveking, Daniel P., Vanags, Laura Z., Lim, Patrick R., Chow, Renee W.Y., Lam, Yuen Ting, Clayton, Zoe, Bao, Shisan, Davies, Michael J., Stadler, Nadina, Celermajer, David S., Stocker, Roland, Bursill, Christina A., Cooke, John P., Ng, Martin K.C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Diabetes Association 2014
Pynciau:
Pathophysiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900553/
https://ncbi.nlm.nih.gov/pubmed/24198286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0417
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