The Role of Factor Inhibiting HIF (FIH-1) in Inhibiting HIF-1 Transcriptional Activity in Glioblastoma Multiforme

Glioblastoma multiforme (GBM) accounts for about 38% of primary brain tumors in the United States. GBM is characterized by extensive angiogenesis induced by vascular growth factors and cytokines. The transcription of these growth factors and cytokines is regulated by the Hypoxia-Inducible-Factor-1(H...

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Detalhes bibliográficos
Main Authors: Wang, Enfeng, Zhang, Chunyang, Polavaram, Navatha, Liu, Fengming, Wu, Gang, Schroeder, Mark A., Lau, Julie S., Mukhopadhyay, Debabrata, Jiang, Shi-Wen, O'Neill, Brian Patrick, Datta, Kaustubh, Li, Jinping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900478/
https://ncbi.nlm.nih.gov/pubmed/24465898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086102
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