The Incidence of Liver Injury in Uyghur Patients Treated for TB in Xinjiang Uyghur Autonomous Region, China, and Its Association with Hepatic Enzyme Polymorphisms NAT2, CYP2E1, GSTM1 and GSTT1

BACKGROUND AND OBJECTIVE: Of three first-line anti-tuberculosis (anti-TB) drugs, isoniazid is most commonly associated with hepatotoxicity. Differences in INH-induced toxicity have been attributed to genetic variability at several loci, NAT2, CYP2E1, GSTM1and GSTT1, that code for drug-metabolizing e...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Xiang, Yang, Ma, Long, Wu, Weidong, Liu, Wei, Li, Yongguang, Zhu, Xia, Wang, Qian, Ma, Jinfeng, Cao, Mingqin, Yao, Xuemei, Yang, Lei, Wubuli, Atikaimu, Merle, Corinne, Milligan, Paul, Mao, Ying, Gu, Jiayi, Xin, Xiumei
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900431/
https://ncbi.nlm.nih.gov/pubmed/24465778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085905
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars