Selective ROCK2 inhibition in focal cerebral ischemia

OBJECTIVE: Rho-associated kinase (ROCK) is a key regulator of numerous processes in multiple cell types relevant in stroke pathophysiology. ROCK inhibitors have improved outcome in experimental models of acute ischemic or hemorrhagic stroke. However, the relevant ROCK isoform (ROCK1 or ROCK2) in acu...

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Detalhes bibliográficos
Main Authors: Hyun Lee, Jeong, Zheng, Yi, von Bornstadt, Daniel, Wei, Ying, Balcioglu, Aygul, Daneshmand, Ali, Yalcin, Nilufer, Yu, Esther, Herisson, Fanny, Atalay, Yahya B, Kim, Maya H, Ahn, Yong-Joo, Balkaya, Mustafa, Sweetnam, Paul, Schueller, Olivier, Poyurovsky, Masha V, Kim, Hyung-Hwan, Lo, Eng H, Furie, Karen L, Ayata, Cenk
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900310/
https://ncbi.nlm.nih.gov/pubmed/24466563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.19
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