Selective ROCK2 inhibition in focal cerebral ischemia

OBJECTIVE: Rho-associated kinase (ROCK) is a key regulator of numerous processes in multiple cell types relevant in stroke pathophysiology. ROCK inhibitors have improved outcome in experimental models of acute ischemic or hemorrhagic stroke. However, the relevant ROCK isoform (ROCK1 or ROCK2) in acu...

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Dettagli Bibliografici
Autori principali: Hyun Lee, Jeong, Zheng, Yi, von Bornstadt, Daniel, Wei, Ying, Balcioglu, Aygul, Daneshmand, Ali, Yalcin, Nilufer, Yu, Esther, Herisson, Fanny, Atalay, Yahya B, Kim, Maya H, Ahn, Yong-Joo, Balkaya, Mustafa, Sweetnam, Paul, Schueller, Olivier, Poyurovsky, Masha V, Kim, Hyung-Hwan, Lo, Eng H, Furie, Karen L, Ayata, Cenk
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2014
Soggetti:
Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900310/
https://ncbi.nlm.nih.gov/pubmed/24466563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.19
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