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Phorbol esters, phospholipase C, and growth factors rapidly stimulate the phosphorylation of a Mr 80,000 protein in intact quiescent 3T3 cells.

Addition of biologically active phorbol esters to intact quiescent 3T3 mouse cells stimulates an extremely rapid (detectable within seconds) phosphorylation of a Mr 80,000 cellular protein (termed "80k"). Phorbol 12,13-dibutyrate enhances 80k phosphorylation in a dose-dependent manner; half-maximal...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Rozengurt, E, Rodriguez-Pena, M, Smith, K A
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1983
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390031/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6316349/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.23.7244
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