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Natural Killer Cells: Tolerance to Self and Innate Immunity to Viral Infection and Malignancy
Natural killer (NK) cells are lymphocytes whose ability to identify and kill virally infected and malignant cells while sparing normal cells was poorly understood until the late 1980’s and the introduction of the “missing self’ hypothesis. According to this hypothesis, downregulation of major histoc...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3900292/ https://ncbi.nlm.nih.gov/pubmed/19835969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2009.10.009 |
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