A frameshift mutation affecting the carboxyl terminus of the simian virus 40 large tumor antigen results in a replication- and transformation-defective virus.
We have constructed a frameshift mutation in the simian virus 40 early region using a novel method of oligonucleotide-directed mutagenesis. The mutated DNA specifies an 84,000-dalton large tumor antigen that consists of approximately equal to 75,000 daltons encoded by the wild-type reading frame and...
Na minha lista:
| 發表在: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1983
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389993/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6316342/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.23.7065 |
| 標簽: |
沒有標簽, 成為第一個標記此記錄!
|