A frameshift mutation affecting the carboxyl terminus of the simian virus 40 large tumor antigen results in a replication- and transformation-defective virus.

Lignende værker

• A functional simian virus 40 origin of replication is required for the generation of a super T antigen with a molecular weight of 100,000 in transformed mouse cells.
  af: Chen, S, et al.
  Udgivet: (1983)
• Reacquisition of a functional early region by a mouse transformant containing only defective simian virus 40 DNA.
  af: Chen, S, et al.
  Udgivet: (1984)
• Simian virus 40-transformed human cells that express large T antigens defective for viral DNA replication.
  af: Gish, W R, et al.
  Udgivet: (1987)
• Genetic and biochemical analysis of transformation-competent, replication-defective simian virus 40 large T antigen mutants.
  af: Manos, M M, et al.
  Udgivet: (1985)
• Pre-crisis mouse cells show strain-specific covariation in the amount of 54-kilodalton phosphoprotein and in susceptibility to transformation by simian virus 40.
  af: Chen, S, et al.
  Udgivet: (1983)