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Genetic analysis of the folding pathway for the tail spike protein of phage P22.
Temperature-sensitive mutations in the gene encoding the trimeric tail spike protein of phage P22 interfere with protein maturation at 39 degrees C. We show here that temperature-sensitive mutations at many sites block the folding pathway prior to accumulation of the partially folded protrimer inter...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1983
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389992/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6227917/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.23.7060 |
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