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Genetic analysis of the folding pathway for the tail spike protein of phage P22.

Temperature-sensitive mutations in the gene encoding the trimeric tail spike protein of phage P22 interfere with protein maturation at 39 degrees C. We show here that temperature-sensitive mutations at many sites block the folding pathway prior to accumulation of the partially folded protrimer inter...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Goldenberg, D P, Smith, D H, King, J
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1983
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389992/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6227917/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.23.7060
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