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Refinement of Protein Structures into Low-Resolution Density Maps using Rosetta

We describe a method based on Rosetta structure refinement for generating high-resolution all-atom protein models from electron cryo-microscopy density maps. A local measure of the fit of a model to the density is used to directly guide structure refinement and to identify regions incompatible with...

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Bibliografiset tiedot
Päätekijät: DiMaio, Frank, Tyka, Michael D., Baker, Matthew L., Chiu, Wah, Baker, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899897/
https://ncbi.nlm.nih.gov/pubmed/19596339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.07.008
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