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Refinement of Protein Structures into Low-Resolution Density Maps using Rosetta
We describe a method based on Rosetta structure refinement for generating high-resolution all-atom protein models from electron cryo-microscopy density maps. A local measure of the fit of a model to the density is used to directly guide structure refinement and to identify regions incompatible with...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3899897/ https://ncbi.nlm.nih.gov/pubmed/19596339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.07.008 |
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