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Separate enrichment analysis of pathways for up- and downregulated genes
Two strategies are often adopted for enrichment analysis of pathways: the analysis of all differentially expressed (DE) genes together or the analysis of up- and downregulated genes separately. However, few studies have examined the rationales of these enrichment analysis strategies. Using both micr...
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Main Authors: | , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
The Royal Society
2014
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3899863/ https://ncbi.nlm.nih.gov/pubmed/24352673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2013.0950 |
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