An Integrated Approach to Uncover Driver Genes in Breast Cancer Methylation Genomes

BACKGROUND: Cancer cells typically exhibit large-scale aberrant methylation of gene promoters. Some of the genes with promoter methylation alterations play “driver” roles in tumorigenesis, whereas others are only “passengers”. RESULTS: Based on the assumption that promoter methylation alteration of...

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Detalhes bibliográficos
Main Authors: Shen, Xiaopei, Li, Shan, Zhang, Lin, Li, Hongdong, Hong, Guini, Zhou, XianXiao, Zheng, Tingting, Zhang, Wenjing, Hao, Chunxiang, Shi, Tongwei, Liu, Chunyang, Guo, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620319/
https://ncbi.nlm.nih.gov/pubmed/23579546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061214
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