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Identifying disease-associated pathways in one-phenotype data based on reversal gene expression orderings
Due to the invasiveness nature of tissue biopsy, it is common that investigators cannot collect sufficient normal controls for comparison with diseased samples. We developed a pathway enrichment tool, DRFunc, to detect significantly disease-disrupted pathways by incorporating normal controls from ot...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5431047/ https://ncbi.nlm.nih.gov/pubmed/28465555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01536-3 |
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