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Electrochemical Assay for the Signal-on Detection of Human DNA Methyltransferase Activity

Strategies to detect human DNA methyltransferases are needed, given that aberrant methylation by these enzymes is associated with cancer initiation and progression. Here we describe a non-radioactive, antibody-free, electrochemical assay in which methyltransferase activity on DNA-modified electrodes...

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Detalhes bibliográficos
Main Authors: Muren, Natalie B., Barton, Jacqueline K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899840/
https://ncbi.nlm.nih.gov/pubmed/24164112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4085918
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