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Transducing methyltransferase activity into electrical signals in a carbon nanotube–DNA device()

This study creates a device where the DNA is electronically integrated to serve as both the biological target and electrical transducer in a CNT–DNA–CNT device. We detect DNA binding and methylation by the methyltransferase M.SssI at the single molecule level. We demonstrate sequence-specific, rever...

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Main Authors: Wang, Hanfei, Muren, Natalie B., Ordinario, David, Gorodetsky, Alon A., Barton, Jacqueline K., Nuckolls, Colin
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399246/
https://ncbi.nlm.nih.gov/pubmed/22822424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C1SC00772F
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