Genetic evidence that Nkx2.2 and Pdgfra are major determinants of the timing of oligodendrocyte differentiation in the developing CNS

In the central nervous system (CNS), oligodendrocyte maturation and axonal myelination occur on a predictable schedule, but the underlying timing mechanisms are largely unknown. In the present study, we demonstrate that Nkx2.2 homeodomain transcription factor is a key regulator for the timing of oli...

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Bibliografiset tiedot
Päätekijät: Zhu, Qiang, Zhao, Xiaofeng, Zheng, Kang, Li, Hong, Huang, Hao, Zhang, Zunyi, Mastracci, Teresa, Wegner, Michael, Chen, Yiping, Sussel, Lori, Qiu, Mengsheng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Company of Biologists 2014
Aiheet:
Stem Cells and Regeneration
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899813/
https://ncbi.nlm.nih.gov/pubmed/24449836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.095323
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