Genetic evidence that Nkx2.2 and Pdgfra are major determinants of the timing of oligodendrocyte differentiation in the developing CNS

In the central nervous system (CNS), oligodendrocyte maturation and axonal myelination occur on a predictable schedule, but the underlying timing mechanisms are largely unknown. In the present study, we demonstrate that Nkx2.2 homeodomain transcription factor is a key regulator for the timing of oli...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhu, Qiang, Zhao, Xiaofeng, Zheng, Kang, Li, Hong, Huang, Hao, Zhang, Zunyi, Mastracci, Teresa, Wegner, Michael, Chen, Yiping, Sussel, Lori, Qiu, Mengsheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2014
Schlagworte:
Stem Cells and Regeneration
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899813/
https://ncbi.nlm.nih.gov/pubmed/24449836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.095323
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