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BRCA1 and its toolbox for the maintenance of genome integrity

The breast and ovarian cancer type 1 susceptibility protein (BRCA1) has pivotal roles in the maintenance of genome stability. Studies support that BRCA1 exerts its tumour suppression function primarily through its involvement in cell cycle checkpoint control and DNA damage repair. In addition, recen...

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Detalhes bibliográficos
Main Authors: Huen, Michael S.Y., Sy, Shirley M.H., Chen, Junjie
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899800/
https://ncbi.nlm.nih.gov/pubmed/20029420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm2831
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