Enhanced FGFR signalling predisposes pancreatic cancer to the effect of a potent FGFR inhibitor in preclinical models

BACKGROUND: Fibroblast growth factor receptor (FGFR) signalling has been implicated in pancreas carcinogenesis. We investigated the effect of FGFR inhibition in pancreatic cancer in complementary cancer models derived from cell lines and patient-derived primary tumour explants. METHODS: The effects...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zhang, H, Hylander, B L, LeVea, C, Repasky, E A, Straubinger, R M, Adjei, A A, Ma, W W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899776/
https://ncbi.nlm.nih.gov/pubmed/24327018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.754
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados