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HIF-1-mediated metabolic reprogramming reduces ROS levels and facilitates the metastatic colonization of cancers in lungs

Hypoxia-inducible factor 1 (HIF-1) has been associated with distant tumor metastasis; however, its function in multiple metastatic processes has not yet been fully elucidated. In the present study, we demonstrated that cancer cells transiently upregulated HIF-1 activity during their metastatic colon...

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Main Authors: Zhao, Tao, Zhu, Yuxi, Morinibu, Akiyo, Kobayashi, Minoru, Shinomiya, Kazumi, Itasaka, Satoshi, Yoshimura, Michio, Guo, Guozheng, Hiraoka, Masahiro, Harada, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899644/
https://ncbi.nlm.nih.gov/pubmed/24452734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03793
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