Metastasis of prostate cancer and melanoma cells in a preclinical in vivo mouse model is enhanced by L-plastin expression and phosphorylation

BACKGROUND: Tumor cell migration and metastasis require dynamic rearrangements of the actin cytoskeleton. Interestingly, the F-actin cross-linking and stabilizing protein L-plastin, originally described as a leukocyte specific protein, is aberrantly expressed in several non-hematopoietic malignant t...

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Main Authors: Riplinger, Selina M, Wabnitz, Guido H, Kirchgessner, Henning, Jahraus, Beate, Lasitschka, Felix, Schulte, Bianca, van der Pluijm, Gabri, van der Horst, Geertje, Hämmerling, Günter J, Nakchbandi, Inaam, Samstag, Yvonne
格式: Artigo
語言:Inglês
出版: BioMed Central 2014
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899628/
https://ncbi.nlm.nih.gov/pubmed/24438191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-10
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